Структурно-функциональные особенности тромбоцитарных интегринов

Авторы

  • Д.Д. ЖЕРНОСЕКОВ (D.D. ZHERNOSSEKOV), д-р биол. наук, доцент Полесский государственный университет, г. Пинск, Республика Беларусь

Ключевые слова:

тромбоциты, интегрины, плазминоген/плазминовая система

Аннотация

В обзоре описаны структурно-функциональные особенности адгезивных белков интегринового семейства, принимающих участие в установлении адгезивных связей тромбоцитов между собой и с другими клетками. Показано модулирующее действие компонентов плазминоген/плазминовой системы на эффективность адгезивного взаимодействия, опосредованнного интегриновыми белками. Рассмотрено действие препаратов, направленных на блокирование интегриновой адгезии.

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Опубликован

2019-06-13

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Раздел

Биологические науки