Forecasting of the of lethal and non-fatal outcomes in senior hypertensive patients

Authors

  • Т.Л. Оленская (T.L. Alenskaya), доцент Vitebsk State Medical University, Vitebsk, Republic of Belarus
  • А.Г. Николаева (A.G. Nikolaeva), доцент Vitebsk State Medical University, Vitebsk, Republic of Belarus
  • В.Е. Руммо (V.E. Rummo), доцент Vitebsk State Medical University, Vitebsk, Republic of Belarus
  • Е.А. Павелко (E.A. Pavelko), студент Vitebsk State Medical University, Vitebsk, Republic of Belarus

Keywords:

hypertension, elderly people, forecasting

Abstract

An integrated approach to the assessment of the health status of older patients with current positions of geriatric syndromes and defined contribution syndrome of cognitive impairment, anxiety-depressive syndrome in the medium-term forecast of the lethal and non-fatal outcomes. Study of survival using the Kaplan-Meier showed statistically significant differences in the examined patients with hypertension in older age groups who are serving on a cottage territorial center of social security of the population, compared with respondents unorganized population (criterion Gehana-Wilcoxon p = 0,04; p = Cox 0,05). The probability of lethal outcomes in patients with hypertension in older age groups has increased 10, 13 times (95% CI 1,2-81,8, p <0.05) if the patient is not taking antihypertensive medications. The presence of cognitive dysfunction syndrome (clock drawing test less than 8 points) increases the risk of death by 1,36 times, anxious-depressive state (geriatric depression scale more than 5 points) – 1,12 times. A model of logistic regression predicting the likely medium-term development of the lethal outcomes in patients with hypertension in older age groups with regard to the main geriatric syndromes is constructed. The sensitivity of the model was 89%, specificity - 94%.

References

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Published

2020-06-29

Issue

Section

Медицинские науки