Patient with hypertension: focus on orthostatic hypotension syndrome and dizziness syndrome
Keywords:
hypertension, elderly people, forecastingAbstract
Influence of age boundary of 60 years on heterogeneity of dynamics of systolic blood pressure level during active orthostatic sample in patients with arterial hypertension is established. In patients with arterial hypertension 60 years and older, statistically significant differences in the dynamics of diastolic blood pressure at the 1st and 15th minutes of the active orthostatic sample were revealed. Statistically significant relationships of dizziness syndrome with dynamics of systolic blood pressure (SAD) level during active orthostatic sample (SAD level at the 1st minute of sample F = 5.39, p = 0.03; SAD in the 5th minute F = 10.40, p = 0,004; SAD in the 10th minute F = 11.81, p = 0,002; with the appearance of cardialgia during the sample F = 10.64, p = 0.003), as well as the level of total cholesterol (F = 4.52, p = 0.04). Models of logistic regression of probable prediction of development of orthostatic hypotension syndrome and dizziness syndrome in patients with arterial hypertension are constructed taking into account complex assessment of results of active orthostatic sample and clinical-laboratory indices.
References
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References
Gupta V., Lipsitz L.A. Orthostatic Hypotension in the Elderly: Diagnosis and Treatment. The American Journal of Medicine. 2007. Vol. 120, pp. 841-847.
Diagnosis and management of orthostatic hypotension. European Federation of Neurological societies. 2011.
Fedorowski A., Melander О. Syndromes of orthostatic intolerance: a hidden danger. Intern Med. 2013 Apr; 273(4), pp. 322-335.
Shibao С., Lipsitz L.A., Biaggioni I. ASH Position Paper: Evaluation and Treatment of Orthostatic Hypotension. The Journal of Clinical Hypertension. V.15, Iss. 3. March 2013, pp. 147–153.
Feldstein C., Wede A.B. Orthostatic hypotension: a common, serious and underrecognized problem in hospitalized patient J Am Soc Hypertens. 2012. Jan-Feb; 6(1), pp. 27-39.
Hajjar, I. Postural blood pressure changes and orthostatic hypotension in the elderly patient: impact of antihypertensive medications / I. Hajjar // Drugs Aging. 2005. – Vol. 22. – № 1. – Р. 55-68.
Olenskaya T.L., Kozlovsky V.I. Metody issledovaniya ortostaticheskikh reaktsiy [Research methods of orthostatic reactions]. Vestnik VSMU. 2002, vol.2, no 1, pp. 26-31. (In Russian)
